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Structural Basis for TGF-β Mimetic Peptide-Induced Signaling Activation Through Molecular Dynamics Simulations.

Int J Mol Sci · 2025 · PMC12785921 · PMID 41515902

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As shown in Figure 10 a–c, TB1 treatment significantly reduced Smad3 protein expression compared with both the control and RTB1 groups, while the level of phosphorylated Smad3 (p-Smad3) decreased, but the change did not reach statistical significance.

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