Association of NT-proBNP and sST2 with Diastolic Dysfunction in Cirrhotic Patients and Its Therapeutic Implications.

Int J Mol Sci · 2025 · PMC12786207 · PMID 41516138

Europe PMC DOI

hedged sentences

0.0540

closest p · 1.1× alpha

0.0540

boldest claim

The sentences

borderline significantp = 0.054so close (0.05 < p ≤ 0.1)

Age emerged as a borderline significant predictor (B = 0.45, SE = 0.24, p = 0.054), suggesting that older individuals may be more likely to exhibit diastolic dysfunction.

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did not reach statistical significanceno p-value reported

Although NT-proBNP values tended to increase with worsening liver disease (higher Child-Pugh class), this association did not reach statistical significance.

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a decreasing trendno p-value reported

When analyzed sSt2 values according to liver disease severity, no significant differences were observed across Child-Pugh classes (H = 0.1604, p = 0.9230), although values displayed a decreasing trend: class A (n = 29)—mean 5.84 ng/mL, median 5.40 ng/mL; class B (n = 5)—mean 5.46 ng/mL, median 5.60 ng/mL; class C (n = 4)—mean 5.33 ng/mL, median 5.25 ng/mL.

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