Structural Damage, Visual Field Loss, and Quality of Life in Optic Disc Drusen: A Case-Control Study with Integrated Data-Driven Phenotypes.

The model’s pseudo-R 2 of 0.34 and highly significant likelihood ratio test ( p < 0.001) indicate a moderate ability to discriminate patients with and without reproducible field defects based on the included covariates.

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Migraine was associated with a trend towards lower QoL (β = −3.1, p = 0.058), suggesting a possible additional burden that did not quite reach statistical significance.

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Axial length, arterial hypertension, and spherical equivalent showed trends in the expected directions (shorter eyes, hypertensive status, and more hyperopic refraction associated with higher odds of VF defects), but did not reach statistical significance.

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