A Pilot Randomized Controlled Trial and Multi-Omics Analysis of Electrolysed Alkaline Water: Impacts on Gut Microbiota and Metabolic Signatures in Hyperuricemia.

Nutrients · 2025 · PMC12787813 · PMID 41515223

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hedged sentences

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closest p · 2.0× alpha

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boldest claim

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marginally significantp < 0.1so close (0.05 < p ≤ 0.1)

Among these metabolites, 1,3-DIMETHYLURIC ACID, 2-Amino-5-chlorobenzoxazole, 4-guanidinobutanoate, 6-Acetamido-3-oxohexanoate, 9-Methyluric acid, Hecogenin, Methyl linolenate, Pristimerin, 8-O-Tigloyldiderroside, Flucytosine, Spicatolide E, and (2-Aminoethyl) phosphonic acid remained marginally significant ( p < 0.1) following multiple-testing correction.

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did not reach statistical significanceno p-value reported

In our study, we observed a modest trend toward increased Faecalibacterium and reduced Bilophila following EAW intake, though this pattern did not reach statistical significance after FDR adjustment.

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