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Optimal timing of cranioplasty post-decompressive craniectomy in traumatic brain injury: a systematic review, meta-analysis, and overview of ongoing trials.

Acta Neurochir (Wien) · 2026 · PMC12789150 · PMID 41507542

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In our analysis, EC was associated with numerically lower shunt-dependent hydrocephalus (7.4% in EC versus 17.1% in LC), though this did not reach statistical significance due to heterogeneity.

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