A large-scale multi-ancestry genome-wide association study of chronic prostatitis/chronic pelvic pain syndrome in men.

While standard differential expression analysis comparing control and treated rats identified 0 genes with adjusted p value < 0.05, a targeted approach focusing on the members of the CP/CPPS-proximal interaction network identified 5 genes with a nominally significant p value < 0.01.

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Two out of the three GWS loci newly identified in the multi-ancestry meta-analysis were also identified in the marginal SNPs EUR analysis ( p < 5 × 10 −6 ), providing more evidence that some of the marginally significant loci do contain relevant information.

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