The predictive value of neutrophil-to-lymphocyte ratio for the occurrence, progression, and mortality of diabetic nephropathy: a systematic review and meta-analysis.

Sci Rep · 2026 · PMC12789594 · PMID 41492002

Europe PMC DOI

hedged sentences

0.0600

closest p · 1.2× alpha

0.0600

boldest claim

The sentences

marginally non-significantP = 0.06so close (0.05 < p ≤ 0.1)

The association with mortality was marginally non-significant (OR = 1.21, 95% CI 0.99–1.48, P = 0.06).

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a marginal trendno p-value reported

Although the association with DN-related mortality did not reach statistical significance, a marginal trend was observed, indicating the need for further investigation.

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an overall trendno p-value reported

However, substantial heterogeneity (I2 > 90%) was observed across studies, indicating that the pooled SMD should be interpreted as reflecting an overall trend rather than a precise estimate of effect size.

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did not reach statistical significanceno p-value reported

Although the association with DN-related mortality did not reach statistical significance, a marginal trend was observed, indicating the need for further investigation.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.