Treatment in acute HIV infection only temporarily preserves monocyte function: a comparative cohort study in adult males.

This reduction in restriction proved highly significant in the other two groups, were we observed a 2.24 and 2.49 fold increase in the AHI-156 and CHI group compared to CG respectively (both p < 0.0001) ( Fig. 3 C).

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In CHI as well as AHI-24 and AHI-156, we observed a trend toward increased mRNA levels of ISGs such as MxA, ISG15, CXCL10, APOBEC3G, and BST2 compared to CG, although these differences did not reach statistical significance ( Fig. 2 E–G).

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