Preoperative MEG reveals differential brain network characteristics in drug-resistant epilepsy patients based on vagus nerve stimulation response.

In accordance with program guidelines and relevant literature, two initial threshold values were set: p < 0.01 to explore more widespread network connectivity alterations, and p < 0.001 to identify highly significant local network components.

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Notably, relative to the HC group, NR-VNS patients displayed more widespread and pronounced FC abnormalities, whereas the R-VNS group showed a trend toward FC normalization.

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