The literature in the field suggests a clear trend for neural interfaces - also called brain-machine interfaces - to possess essential features such as softness (decreasing the mechanical mismatch between the synthetic material and the neural tissue), reduced dimension (reaching cellular resolution and volumetric distribution, reducing invasiveness, improving membrane coupling), freestanding or wireless capabilities (improving resolution and volumetric distribution, reducing invasiveness), and optimal material and coating composition (improving biocompatibility and electrodes impedance) 1 – 6 .
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Advancing neural interfaces: a framework for the fabrication and characterization of freestanding micro-nanodevices.
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