Aryl Hydrocarbon Receptor Ligands Drive Pancreatic Cancer Initiation and Progression through Protumorigenic T-cell Polarization.

Cancer Discov · 2026 · PMC12793834 · PMID 40905825

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a strong trendno p-value reported

Smokers demonstrated a strong trend toward increased CYP1A1 and CYP1B1 expression in bulk pancreatic tissue, suggesting a difference in AHR activation in the pancreas of smokers (Supplementary Fig.

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