Barely Significant
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The impact of growth hormone (GH) on immunosenescence: exploring the role of B and T cells.

Pituitary · 2026 · PMC12795870 · PMID 41524828

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a decreasing trendno p-value reported
Differences were observed in the cytotoxic T cell compartment, where effector memory (CD8 + EM) and central memory (CD8 + CM) T cells showed a decreasing trend in GHR-/- mice but did not reach statistical significance.

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an increasing trendno p-value reported
While FO B cells showed an increasing trend (Fig. 3 b), the difference did not reach significance in the blood of GHR-/- mice relative to controls.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.