Barely Significant
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Gut proteome and microbiome alterations: Analysis of transverse colon samples from pathologically confirmed Alzheimer's disease patients.

Alzheimers Dement · 2026 · PMC12796839 · PMID 41527485

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hedged sentence
0.0130
closest p · 0.3× alpha
0.0130
boldest claim

The sentences

modest significanceP = 0.013actually significant
84 , 85 Downregulated proteins included C2, C3, C4A, C4B, C5, C6, and C7, with C5, C6, and CFB showing modest significance (adjusted P s = 0.050–0.051) and CFI, a key regulator, showing the most significant reduction (adjusted P = 0.013).

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