<i>Tet2</i> deficiency promotes IgG1+ B-cell expansion and differentiation blockade through deregulation of the <i>Nfkbia</i>-c-Rel axis.

The cell frequencies of IgG1+ B‐cells were significantly lower in Tet2 ‐KO cells compared to Tet2 ‐WT cells (Figure 2B ); however, a slight decrease was noticed in the cell number of IgG1+ Tet2 ‐KO but did not reach statistical significance (Supporting Information S1: Figure 1D ).

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