Central and peripheral factors moderating pain effects on motor control and disability in chronic lumbosacral radicular pain.

J Neuroeng Rehabil · 2025 · PMC12797704 · PMID 41353377

Europe PMC DOI

hedged sentences

0.0610

closest p · 1.2× alpha

0.0760

boldest claim

The sentences

marginally significantp = 0.061so close (0.05 < p ≤ 0.1)

Specifically, at the 16th percentile of N80, pain duration strongly predicted disability (β = 0.285, 95% CI [0.116, 0.453], p = 0.002); at the 50th percentile, the effect was moderate and marginally significant (β = 0.088, 95% CI [−0.004, 0.181], p = 0.061); and at the 84th percentile, the association was negligible and not significant (β = −0.028, 95% CI [−0.158, 0.102], p = 0.666).

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did not reach statistical significancep = 0.072so close (0.05 < p ≤ 0.1)

The interaction between pain duration and paraspinal MEPs did not reach statistical significance (β = −0.003, 95% CI [−0.006, 0.0003], p = 0.072).

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a marginal trendp = 0.076so close (0.05 < p ≤ 0.1)

In contrast, greater contralateral abdominal muscle activation during the APA phase showed a marginal trend toward a stronger association between pain and motor control impairment (interaction p = 0.076).

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