SETD1A regulates psychiatric gene networks involved in genomic stability and synaptic function in rare and sporadic schizophrenia.

Although SETD1A_CST peaks exhibited more specific accumulation on promoters than SETD1A_Atlas peaks, there was a highly significant overlap of SETD1A peaks between the two antibodies around TSSs in each of the three brains (Supplementary Fig. 5h ).

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H3K4me1/2 levels were also reduced, although these did not reach statistical significance.

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