Again, 2-way ANOVA confirmed that both PCB exposure (IL-8: P = .041, IL-10: P = .007) and the interaction between PCB exposure and AhR blockade (IL-8: P = .015, IL-10: P = .005) were statistically significant ( P < .05), while AhR blockade alone did not reach statistical significance (IL-8: P = .053, IL-10: P = .702).
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Aroclor 1254 inhibits anti-inflammatory macrophage polarization through an AhR-dependent mechanism.
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