Association of circulating immune cell phenotypes and peripheral inflammatory biomarkers with depressive symptoms in the Framingham Heart Study.

Psychoneuroendocrinology · 2026 · PMC12801172 · PMID 41349492

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a positive trendno p-value reported

There were no significant associations observed between inflammatory markers and depressive symptoms (CES-D score 16 or higher); however, a positive trend with higher IL-17C levels was observed, which did not meet multiple test correction.

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a negative trendno p-value reported

We observed a negative trend in CES-D score with higher CD8Tc17/CD8Treg ratio, but it did not meet multiple test correction.

also in 4,201 other papers

Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.