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Low-Dose Mavacamten Initiation in Obstructive Hypertrophic Cardiomyopathy: A Real-World Study in China.

Cardiovasc Ther · 2026 · PMC12801204 · PMID 41542284

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Notably, the mid‐LVO subgroup exhibited numerically smaller reductions in resting and provoked gradients compared with LVOTO patients, with a clinically relevant difference trend that did not reach statistical significance likely due to MVO′s limited sample size, suggesting potentially diminished mavacamten efficacy in mid‐cavitary obstruction that warrants validation in larger cohorts.

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Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.