Multiview deep-learning-enabled histopathology for prognostic and therapeutic stratification in stage II colorectal cancer: A retrospective multicenter study.

Although no significant interaction was observed in the internal dataset, significant or near-significant interactions were identified in two external cohorts ( S6 Table ).

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We further evaluated the stratification performance of the model under multiple fixed thresholds, and the results show that MVNet achieves highly significant stratification across all datasets, regardless of whether the thresholds are fixed or dataset-specific ( S14 Fig and S3 Table ).

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