Is the superior septal approach a safe alternative to conventional left atriotomy for mitral valve surgery? Evidence from a systematic review and meta-analysis.

BMC Cardiovasc Disord · 2025 · PMC12801893 · PMID 41350631

Europe PMC DOI

hedged sentences

0.0600

closest p · 1.2× alpha

0.3100

boldest claim

The sentences

borderline significancep = 0.06so close (0.05 < p ≤ 0.1)

15/419), but the pooled risk ratio showed borderline significance (RR = 1.85, 95% CI 0.97–3.51; p = 0.06; I2=0%) (Figure S13).

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a nonsignificant trendp = 0.31not close (p > 0.1)

Respiratory complications showed a nonsignificant trend favoring SSA but with substantial heterogeneity (RR = 0.41, 95% CI 0.07–2.29; p = 0.31; I2=65%) (Figure S15).

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did not reach statistical significanceno p-value reported

AF tended to decrease after the SSA but did not reach statistical significance, while the CLA group showed little change in postoperative AF rates.

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