Exercise haemodynamics in pulmonary hypertension - a prospective pressure-volume loop study on right ventricular adaptation and prognosis.

However, Ea did not differ significantly between the two groups, although the difference in ΔEa between the RV adaptation groups almost reached significance in the ANOVA factorial analysis ( p = 0.073).

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Clinically, these patients exhibit reduced exercise capacity, increased dyspnoea, and a markedly higher rate of clinical deterioration than the homeometric group, with a clear trend towards poorer survival (an effect we could only approximate owing to the relatively short observation period).

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