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Tumor microenvironment differences between diagnostic and relapsed classic Hodgkin lymphoma revealed by scRNA-seq.

Blood Adv · 2026 · PMC12803924 · PMID 40924921

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Consistent with our previous IMC-based findings, 16 the overall proportion of B cells tended to be lower in early-relapse samples than diagnostic and late-relapse samples ( supplemental Figure 1 A), although this difference did not reach statistical significance, likely due to limited sample size.

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