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Expanding the therapeutic horizon of <sup>177</sup>Lu-DOTATATE: a review of current evidence.

Nagoya J Med Sci · 2025 · PMC12805127 · PMID 41550194

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51 Mirvis et al reported that patients with bronchial NETs who were treated with 177 Lu-DOTATATE had a median PFS of 18 months, which is longer than the 12 months for those treated with 90 Y-DOTATATE, although the difference did not reach statistical significance. 52 Furthermore, 177 Lu-DOTATATE was effective in alleviating the symptoms of carcinoid syndrome, including reductions in bowel movement frequency, flushing, and urinary 5-hydroxyindoleacetic acid excretion.

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