Replacing Helper Lipids With Cationic Lipids Enhances mRNA Lipid Nanoparticles Stability in Solution.

Adv Sci (Weinh) · 2026 · PMC12806310 · PMID 41164988

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showed a trendno p-value reported

Notably, RNA electrophoresis of the LNP samples on day 12 showed a trend of increase in percentages of intact mRNA for the LNPs with 4.7% DOTAP.

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