Although nivolumab showed a numerical trend towards improved OS, this difference warrants cautious interpretation.
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A network meta-analysis of first-line treatment options for patients with Child-Pugh class B functional hepatocellular carcinoma: comparison of efficacy and safety.
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Additionally, although the difference was not statistically significant, nivolumab showed a trend towards lower discontinuation rates compared to sorafenib due to toxicity or clinical deterioration.