Comparative safety and short-term outcomes of intraoperative radiotherapy versus neoadjuvant chemoradiotherapy in locally advanced rectal cancer: a retrospective study.

Front Surg · 2025 · PMC12808456 · PMID 41550093

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did not reach statistical significanceno p-value reported

8.6%, P = 0.060), though the difference did not reach statistical significance.

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an increasing trendno p-value reported

Although perioperative safety in the IORT cohort remained acceptable overall, certain complications exhibited an increasing trend, underscoring the need for more rigorous perioperative risk-management strategies.

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