A comparative study of anticoagulation combined with different catheter-directed thrombolysis strategies (urokinase catheter-directed vs. alteplase infusion) in the treatment of intermediate-risk pulmonary embolism.

Front Cardiovasc Med · 2025 · PMC12808480 · PMID 41552686

Europe PMC DOI

hedged sentence

0.0880

closest p · 1.8× alpha

0.0880

boldest claim

The sentences

did not reach statistical significanceP = 0.088so close (0.05 < p ≤ 0.1)

Although both treatment regimens significantly improved thrombus burden, RV function, and myocardial injury markers, the reduction in NT-proBNP in the rt-PA group did not reach statistical significance ( P = 0.088).

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