Adaptogenic Effects of Mushroom Blend Supplementation on Stress, Fatigue, and Sleep: A Randomised, Double-Blind, and Placebo-Controlled Trial.

Brain Behav · 2026 · PMC12808922 · PMID 41540766

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an increasing trendno p-value reported

Biomarker analysis showed reductions in cortisol, adrenocorticotropic hormone, norepinephrine, and C‐reactive protein, with an increasing trend in morning melatonin levels.

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did not reach statistical significanceno p-value reported

While other parameters did not reach statistical significance, the overall PSQI score trend suggests enhanced sleep efficiency and reduced sleep disturbances, which are crucial for long‐term sleep health.

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