Elenbecestat and Compound 89 Potently Inhibit BACE1 but Not BACE2 When Subchronically Dosed in Non-Human Primates.

Proteomics · 2026 · PMC12809003 · PMID 41310967

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did not reach statistical significanceno p-value reported

Due to a higher variance within the vehicle group, VCAM‐1 immunoblot data for verubecestat compared to vehicle treatment did not reach statistical significance, but the effect sizes for all treatment groups were similar to the proteomic data.

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