Understanding dopaminergic dose reduction following STN-DBS: mediation analysis.

BMJ Neurol Open · 2026 · PMC12815016 · PMID 41561678

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0.0650

closest p · 1.3× alpha

0.0650

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The sentences

showed a trendp=0.065so close (0.05 < p ≤ 0.1)

Sensorimotor STN overlap was not directly linked to LEDD reduction but was positively associated with motor improvement (β=0.34, p=0.001), which showed a trend-level effect on LEDD reduction (β=0.16, p=0.065).

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