Serum cytokines predict response and survival in esophageal squamous cell carcinoma receiving chemoradiotherapy combined with anti-PD-1 antibody: analyses of two phase II clinical trials.

J Immunother Cancer · 2026 · PMC12815036 · PMID 41526165

Europe PMC DOI

hedged sentence

0.0640

closest p · 1.3× alpha

0.0640

boldest claim

The sentences

showed a trendp=0.064so close (0.05 < p ≤ 0.1)

Baseline C-C motif chemokine ligand 4 (CCL4) also showed a trend toward correlation with poor survival (HR, 2.02; 95% CI 0.96 to 4.26; p=0.064) ( figure 1C and online supplemental table 3 ).

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