28 , 30 Analysis of tumor volume and weight revealed that both anti-IGSF9 and LALAPG-mutant anti-IGSF9 treatments showed a trend toward reduced tumor growth compared with mIgG control, although the statistical analysis showed no significant differences ( online supplemental sFigure 7D–G ), likely due to high interindividual variability.
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Tumor-associated macrophages educated by IGSF9 exhibit a senescence-associated secretory phenotype to promote tumor immune escape.
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