A systematic review and meta-analysis assessing the influence of histone deacetylase 6 inhibition on brain infarction and neurological function following acute ischaemic stroke in rodent models.

J Cereb Blood Flow Metab · 2026 · PMC12815625 · PMID 41549345

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did not reach statistical significanceno p-value reported

All reported a trend towards smaller cerebral infarctions in animals receiving HDAC6 inhibitors than controls, however this did not reach statistical significance in all studies ( Table 2 ).

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