The NMDAR/TRPM4 death complex is a major promoter of disease progression in the 5xFAD mouse model of Alzheimer's disease.

Mol Psychiatry · 2026 · PMC12815682 · PMID 40858778

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showed a trendno p-value reported

During the last training session, 5xFAD mice treated with FP802 already showed a trend—albeit not statistically significant—towards shorter escape latencies to reach the hidden platform compared to vehicle-treated mice (Fig. 2A ).

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