<i>Fusobacterium nucleatum</i> drives CD40-mediated dendritic cell activation and Th17/Treg imbalance to exacerbate intestinal inflammation in Crohn's disease.

Rarefaction curves revealed significantly diminished bacterial diversity in CD fecal microbiota compared to healthy subjects ( Figure 1B ), while a similar trend was observed in mucosal samples, though it did not reach statistical significance ( Figure 1B ).

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