MALT1 in cerebrospinal fluid: a prognostic biomarker and potential therapeutic target in Alzheimer's disease.

Front Neurol · 2025 · PMC12815869 · PMID 41567547

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highly significantno p-value reported

Notably, cerebrospinal fluid (CSF) metabolites play a crucial role in the early diagnosis of AD, making their investigation highly significant.

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did not reach statistical significanceno p-value reported

Other metabolites, such as ascorbate, leucine, and myo-inositol, showed nominal associations but did not reach statistical significance after multiple-testing correction ( Supplementary Tables S2, S3 ).

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