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Mesenchymal stem cell-based therapy for osteoarthritis: a systematic review and meta-analysis of clinical outcomes and functional recovery.

Front Cell Dev Biol · 2025 · PMC12816338 · PMID 41567976

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The study by Tan YH 2013 showed a pronounced treatment effect with a mean difference of −5.32 (95% CI: −5.91 to −4.73), while Vega A 2015 demonstrated a similar trend with a mean difference of −6.00 (95% CI: −13.55 to 1.55), though the latter did not reach statistical significance likely due to smaller sample size.

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