PRC2-Related Epigenetic Age Acceleration in Acute Myeloid Leukemia with DNMT3A and IDH2 Mutations.

Adv Biol (Weinh) · 2026 · PMC12817234 · PMID 41556261

Europe PMC DOI

hedged sentence

0.2200

closest p · 4.4× alpha

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boldest claim

The sentences

did not reach statistical significancep = 0.22not close (p > 0.1)

In the DNAm‐related gene‐mutated CN‐AML subgroup, patients in the High AdaptAge group tended to exhibit higher OS compared to the Low AdaptAge group, compared to the other groups of full TCGA AML and CN‐AML, though this difference did not reach statistical significance ( p = 0.22, log‐rank test).

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