Cross-platform comparison of gene expression-based cancer molecular subtyping reveals discrepancies with exome capture methods.

NPJ Precis Oncol · 2025 · PMC12819530 · PMID 41422185

Europe PMC DOI

hedged sentence

0.0610

closest p · 1.2× alpha

0.0610

boldest claim

The sentences

did not reach statistical significanceP = 0.061so close (0.05 < p ≤ 0.1)

Differences in overall survival in patients with basal-like tumors compared to classical tumors did not reach statistical significance using exome capture (log-rank P = 0.061), whereas with whole transcriptome it was significantly shorter (log-rank P < 0.0001).

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