Meta-analysis of the effects of probiotic supplementation on bone turnover markers in middle-aged and elderly patients with osteoporosis.

Front Cell Infect Microbiol · 2025 · PMC12819596 · PMID 41574289

Europe PMC DOI

hedged sentence

0.0800

closest p · 1.6× alpha

0.0800

boldest claim

The sentences

did not reach statistical significancep=0.08so close (0.05 < p ≤ 0.1)

N-terminal telopeptide (NTX) was reported in six trials, showing a downward trend that approached but did not reach statistical significance (MD = −9.2 nmol BCE/mmol creatinine; 95% CI: −19.8 to 1.3; p=0.08).

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