Barely Significant
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CHI3L1 monoclonal antibody therapy mitigates cognitive impairment by inhibiting neuroinflammation through ERK and NF-κB pathway in Tg2576 mice.

Front Mol Neurosci · 2025 · PMC12819630 · PMID 41573517

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a decreasing trendno p-value reported
Although the reduction in TNF-α expression did not reach statistical significance, a decreasing trend was evident, suggesting that an increased number of experimental replicates may reveal a statistically significant effect.

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