Predictive value of neutrophil-to-lymphocyte ratio, platelet-to-lymphocyte ratio, and monocyte-to-lymphocyte ratio for three-year survival in patients with early esophageal cancer undergoing endoscopic submucosal dissection.

When NLR was categorized into quartiles, compared with the first quartile, the fourth quartile had a significantly higher risk of death (HR = 4.643, 95% CI 1.323–16.293, P = 0.017), while the second and third quartiles showed increased risk (HR = 1.710 and 3.065, respectively) but did not reach statistical significance (P > 0.05).

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After false discovery rate (FDR) correction, some borderline significant interaction effects became non-significant, indicating that the conclusions from the interaction analyses are exploratory and require further validation in studies with larger sample sizes. 5.

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