Relative telomere length and senescence-associated inflammatory cytokines as blood-based prognostic markers in patients with advanced or resectable gastro-oesophageal adenocarcinoma.

and the scaled IL8 term was highly significant in the multivariate model (HR = 1.087, 90% CI = 1.048–1.128 p < 0.001).

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In the advanced disease study, the proportion of patients with detectable IL1β was significantly higher in gastro-oesophageal junction cancers than in other sites ( p = 0.006) and IL12 was detected more frequently in gastric cancers, although this was borderline significant ( p = 0.051).

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Although the Kaplan–Meier plot for RFS does appear to suggest a survival advantage in the high RTL group, the relationship did not reach statistical significance in Cox regression at the 2-sided 2.5% level (Table 2 , p = 0.313).

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