Targeting STEC-induced edema disease in weaned piglets: prophylactic oral phage P-GXEC-L2P5 attenuates bacterial colonization, toxin production, and endothelial damage.

The PPG demonstrated highly significant elevation in fluorescence intensity values ( P < 0.01) for both the superior mesenteric artery and jugular vein compared with the PG, while showing no statistically significant differences compared with the NG (Figures 8 B, C).

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In this study, the clinical parameters of the PG showed a trend of progressive deterioration, while piglets pretreated with phage P-GXEC-L2P5 exhibited rapid recovery after STEC infection, which was similar to that of the NG.

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