NOX2-Driven Oxidative Stress Promotes EndMT and Uncouples Angiogenesis-Osteogenesis at the Bone-Implant Interface in Diabetes.

Adv Sci (Weinh) · 2026 · PMC12822455 · PMID 41214866

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did not reach statistical significanceno p-value reported

The canonical JAK–STAT signaling pathway itself did not reach statistical significance (FDR ≥0.05); however, several representative components of this axis (Jak1, Jak3, Socs3, and Il6ra) showed directionally concordant down‐regulation trends in EC‐KO (Table S1 and Figure S15 , Supporting Information).

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