Physical Activity Is Inversely Associated with Clinical Exacerbation in Patients with Crohn's Disease in Remission: A Prospective Cohort Study.

Dig Dis · 2026 · PMC12823096 · PMID 41379730

Europe PMC DOI

hedged sentences

0.0530

closest p · 1.1× alpha

0.0780

boldest claim

The sentences

borderline significantp = 0.053so close (0.05 < p ≤ 0.1)

PA and PROMs in Cross-Sectional Analysis At baseline, patients performing high PA reported fewer occurrences of liquid/soft stools compared to those with low PA, with a borderline significant difference (median 0 [0–1] vs. 0 [0–2], p = 0.053).

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did not reach statistical significancep = 0.078so close (0.05 < p ≤ 0.1)

43.5%, p = 0.020), as well as high fatigue levels although it did not reach statistical significance (20.8% vs. 40.9%, p = 0.078) (shown in Fig. 2 ).

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borderline significanceno p-value reported

In a multivariable regression analysis assessing each PA type, adjusting for age and sex, only high-resistance PA showed a borderline significant association with lower pain interference (OR = 0.29, 95% CI 0.09–0.98) and a borderline significance association with better ability to participate in social roles (OR = 0.30, 95% CI 0.09–1.02) (online suppl.

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