Contributions of selenoproteins to breast cancer etiology and racial disparity.

The expected relationship between the minor SELENOF allele and lower SELENOF levels was only observed in HER2-positive tumor tissues, and this relationship was not seen in HER-negative tissues, although he relationship failed to reach statistical significance due to correction for multiple comparisons.

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This may be significant as there have been several reports of lower selenium levels in African American populations, including those in Chicago from whose tissues were used to generate the TMA described here [ 25 , 38 – 40 ].

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