Although ACE inhibitor use showed a positive association with creatinine increase in both models, this effect did not reach statistical significance ( p > 0.05).
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Trimetazidine and allopurinol for the prevention of Contrast-associated acute kidney injury in elective percutaneous coronary intervention: a randomized controlled trial.
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0.0500
The sentences
It may also indicate a possible trend toward benefit with trimetazidine and allopurinol, although the study was not powered to establish statistical significance.