Barely Significant
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Trimetazidine and allopurinol for the prevention of Contrast-associated acute kidney injury in elective percutaneous coronary intervention: a randomized controlled trial.

Eur J Clin Pharmacol · 2026 · PMC12823743 · PMID 41566038

2
hedged sentences
0.0500
closest p · 1.0× alpha
0.0500
boldest claim

The sentences

did not reach statistical significancep > 0.05actually significant
Although ACE inhibitor use showed a positive association with creatinine increase in both models, this effect did not reach statistical significance ( p > 0.05).

also in 74,032 other papers

a possible trendno p-value reported
It may also indicate a possible trend toward benefit with trimetazidine and allopurinol, although the study was not powered to establish statistical significance.

also in 939 other papers

Quoted from the open-access full text in Europe PMC under the licence the publisher applied. The sentence is reproduced exactly as published; the emphasis is ours.