Gut microbiota-derived metabolite isovalerylcarnitine modulates salt sensitivity of blood pressure and incident hypertension: a multicenter dietary salt intervention trial.

Nat Commun · 2025 · PMC12824221 · PMID 41453903

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A total of 68 salt-related metabolites showed nominally significant associations with various salt-related gut-microbial species and functional pathways ( p < 0.05), indicating that the changes in gut microbiota may contribute to the changes in metabolite (Supplementary Figs. 8 and 9 ).

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